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Epidemiological and Genomic Landscape of Azole Resistance Mechanisms in Aspergillus Fungi

20 Sept 2016

Abstract excerpt

Invasive aspergillosis is a life-threatening mycosis caused by the pathogenic fungus Aspergillus. The predominant causal species is Aspergillus fumigatus, and azole drugs are the treatment of choice. Azole drugs approved for clinical use include itraconazole, voriconazole, posaconazole, and the recently added isavuconazole. However, epidemiological research has indicated that the prevalence of azole-resistant A....

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PMID: 27708619
DOI: 10.3389/fmicb.2016.01382

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