Article

A minimal transcriptomic signature predicts intravascular tumor extension in renal cell carcinoma

2026-03-09

Abstract excerpt

<h4>ABSTRACT</h4> Renal cell carcinoma (RCC) with venous tumor thrombus, termed renal intravascular tumor extension (RITE), is associated with aggressive behavior and poor clinical outcomes. Yet, its underlying molecular determinants remain incompletely defined. We analyzed RNA sequencing data from three independent RCC cohorts comprising 721 samples. Two cohorts included matched samples of index tumor, tumor thr...

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Literature Corpus work: 6e563c5a-cc2b-55ee-bf1e-5afb054da21c
DOI: 10.64898/2026.03.05.709839

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