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Renal cell carcinoma histologic subtypes exhibit distinct transcriptional profiles

23 Apr 2024

Abstract excerpt

Molecular profiling of clear cell renal cell carcinoma (ccRCC) tumors of patients in a clinical trial has identified distinct transcriptomic signatures with predictive value, yet data in non-clear cell variants (nccRCC) are lacking. We examined the transcriptional profiles of RCC tumors representing key molecular pathways, from a multi-institutional, real-world patient cohort, including ccRCC and centrally...

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PMID: 38652565
DOI: 10.1172/jci178915

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