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Article

Integrative genomic study of Chinese clear cell renal cell carcinoma reveals features associated with thrombus.

Nature communications - 6 Feb 2020

Wang Xiang-Ming, Lu Yang, Song Yi-Meng, Dong Jun, Li Ruo-Yan, Wang Guo-Liang, Wang Xu, Zhang Shu-Dong, Dong Zhou-Huan, Lu Min, Wang Shi-Yu, Ge Li-Yuan, Luo Guang-Da, Ma Run-Zhuo, George Rozen Steve, Bai Fan, Wu Di, Ma Lu-Lin

Abstract excerpt

Clear cell renal cell carcinoma (ccRCC) is a heterogeneous disease with features that vary by ethnicity. A systematic characterization of the genomic landscape of Chinese ccRCC is lacking, and features of ccRCC associated with tumor thrombus (ccRCC-TT) remain poorly understood. Here, we applied whole-exome sequencing on 110 normal-tumor pairs and 42 normal-tumor-thrombus triples, and transcriptome sequencing on...

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Identifiers

PMID: 32029730
DOI: 10.1038/s41467-020-14601-9
PMCID: PMC7005298

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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