Article

Morphological analysis of the Axon Initial Segment in novel monogenic rat models of Autism Spectrum Disorder and Intellectual Disability

2020-01-01

Abstract excerpt

Monogenic mutations in synaptic proteins are known to cause severe and low functioning cases of autism spectrum disorder and intellectual disability (ASD/ID) (Wright et al., 2018). One of the most prevalent monogenic causes of moderate to severe non-syndromic and syndromic ID with a high co-morbidity of seizures and altered sensory processing is SYNGAP1 haploinsufficiency (Hamdan et al., 2009; Hoischen et al., 201...

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Literature Corpus work: 6dbea271-16f4-5bd4-bdb7-706b16b2d0ee
DOI: 10.7488/era/1295

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