Article

CRISPR-Cas Associated Cells and Animal Mediated Biomedical Modelling

2024-02-02

Abstract excerpt

Gene editing is now easy to make new disease models through in-vivo and in vitro tests. It can potentially be used to make animals with single-gene or multiple-gene changes. The mutant strains with changed germlines are no longer needed with in vivo gene editing, which uses the CRISPR-Cas9 system to target cells of interest in their normal tissues. Whereas, the AAVs and other viral vectors have made it possible to...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6d9ce6d1-0061-5d0d-a4c0-22874eee9870
DOI: 10.20944/preprints202402.0027.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

CRISPR-Cas Associated Cells and Animal Mediated Biomedical ModellingDOI 10.20944/preprints202402.0027.v1Read

Toward a CRISPR Picture: Use of CRISPR/Cas9 to Model Diseases in Human Stem Cells In Vitro.Semantic proximity Read

CRISPR-mediated genome editing and human diseasesSemantic proximity Read

In vivo and in vitro disease modeling with CRISPR/Cas9.Semantic proximity Read

Creating cell lines for mimicking diseases.Semantic proximity Read

A new era of gene editing for the treatment of human diseasesSemantic proximity Read

Modeling human disease in rodents by CRISPR/Cas9 genome editing.Semantic proximity Read

Gene and cell therapy of human genetic diseases: Recent advances and future directionsSemantic proximity Read

Investigating human disease using stem cell models.Semantic proximity Read

Exploiting CRISPR Cas9 in Three-Dimensional Stem Cell Cultures to Model DiseaseSemantic proximity Read

Genome editing for the reproduction and remedy of human diseases in mice.Semantic proximity Read

Using CRISPR to understand and manipulate gene regulation.Semantic proximity Read

Induced Pluripotency and Gene Editing in Disease Modelling: Perspectives and ChallengesSemantic proximity Read