Article
In vivo and in vitro disease modeling with CRISPR/Cas9.
Briefings in functional genomics - 1 Jan 2017
Kato Tomoko, Takada Shuji
Abstract excerpt
In the past few years, extensive progress has been made in the development of genome-editing technology. Among several genome-editing tools, the clustered regularly interspaced short palindrome repeat-associated Cas9 nuclease (CRISPR/Cas9) system is particularly widely used owing to the ease of sequence-specific nuclease construction and the highly efficient introduction of mutations. The CRISPR/Cas9 system was...
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