Article

Global Transcriptome Profile of the Developmental Principles of in Vitro iPSC-to-Motor Neuron Differentiation

2020-11-19

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<title>Abstract</title> <p>BackgroundHuman induced pluripotent stem cells (iPSC) have opened new avenues for regenerative medicine. Consequently, iPSC-derived motor neurons have emerged as potentially viable therapies for spinal cord injuries and neurodegenerative disorders including Amyotrophic Lateral Sclerosis. However, direct clinical application of iPSC bears in itself the risk of tumorigenesis and other unf...

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Literature Corpus work: 6d99be92-db5c-50fe-9d0a-a9e4f960ed3e
DOI: 10.21203/rs.3.rs-108453/v1

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