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Combination of blockade of endothelin signalling and compensation of IGF1 expression confers protective effects on degenerating retina

2023-08-07

Abstract excerpt

<title>Abstract</title><p>Retinitis pigmentosa (RP) and macular dystrophy (MD) cause severe retinal dysfunction, from which 1 in 4,000 people suffer worldwide. This disease is currently assumed to be intractable because effective therapeutic methods have not been established, regardless of genetic or sporadic traits. Here, we took advantage of RP model mice in which the<italic>Prominin-1</italic>(<italic>Prom1</it...

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Literature Corpus work
6d964ea5-277e-5633-9ad1-01ca1652b2a1
DOI
10.21203/rs.3.rs-3194107/v1
Open publication

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Combination of blockade of endothelin signalling and compensation of IGF1 expression confers protective effects on degenerating retinaDOI 10.21203/rs.3.rs-3194107/v1
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