Article

Glucose-Sensing ChREBP Protein in the Pathogenesis of Diabetic Retinopathy

2024-12-05

Abstract excerpt

Glucose-sensing ChREBP and MondoA are transcriptional factors involved in lipogenic, inflammatory, and insulin signaling pathways implicated in metabolic disorders; however, limited ocular studies have been conducted on these proteins. We aimed to investigate the potential role of ChREBP in pathogenesis of diabetic retinopathy (DR). We used diabetic human and mouse retinal cryosections analyzed by immunohistochemi...

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Literature Corpus work: 37ccb637-c8f5-51b1-8d77-f38fe168074d
DOI: 10.1101/2024.12.04.626828

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