Article

Differential Promoter Methylation of MMP-9 and E-Cadherin Genes in CLL: Evidence for a Pathogenic Role of MMP-9 Hypomethylation

2026-02-25

Abstract excerpt

<h4>Background: </h4> /Objectives: Chronic lymphocytic leukemia (CLL) is characterized by genetic and ep-igenetic alterations. This study aimed to assess the methylation status of E-Cadherin and MMP-9 gene promoters and to explore their relationships with disease pathogenesis and hematological parameters in CLL patients. <h4>Methods:</h4> A case–control study was conducted including 70 newly diagnosed CLL patients...

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Literature Corpus work: 6d60011f-d806-5f14-ab2c-272fd39c80e5
DOI: 10.20944/preprints202602.1546.v1

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