Article

Time-series RNA-Seq and data-driven network inference unveil dynamics of cell activation, survival and crosstalk in Chronic Lymphocytic Leukaemia in vitro models

2025-05-07

Abstract excerpt

<title>Abstract</title> How do cancer cells respond to their environment, and what are the key regulators behind their behaviour? While immune cell reprogramming in the tumour microenvironment (TME) has been extensively studied, the dynamic regulatory changes within cancer cells in response to interactions with immune cells remain poorly understood. In Chronic Lymphocytic Leukaemia (CLL), this knowledge gap li...

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Literature Corpus work: 6d1419b8-c630-509b-9bf5-f238e172266c
DOI: 10.21203/rs.3.rs-6479966/v1

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