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Immune dysregulation and prognostic signatures associated with Epstein–Barr virus in acute lymphoblastic leukemia: an integrated transcriptomic and single-cell analysis

2025-10-22

Abstract excerpt

<title>Abstract</title> <p> Background Epstein–Barr virus (EBV) is associated with lymphoid malignancies; however, its contribution to acute lymphoblastic leukemia (ALL) is unclear. Therefore, we investigated the associations between EBV-related transcriptional activity and immune remodeling in ALL across publicly available cohorts. Methods This study integrated transcriptomics, weighted gene co-expression netwo...

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Literature Corpus work
9cf5f9cf-9f3b-5126-8fee-4d37fac5b70a
DOI
10.21203/rs.3.rs-7725271/v1
Open publication

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Immune dysregulation and prognostic signatures associated with Epstein–Barr virus in acute lymphoblastic leukemia: an integrated transcriptomic and single-cell analysisDOI 10.21203/rs.3.rs-7725271/v1
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