Article

A <i>FLOT1</i> host regulatory allele is associated with a recently expanded <i>Mtb</i> clade in patients with tuberculosis

2022-02-08

Abstract excerpt

The outcome of infectious diseases may depend on the interaction between human and pathogen genomic variations. We explore this relationship in tuberculosis (TB) by conducting a genome-to-genome (g2g) study of paired genomes from humans and the infectious agent Mycobacterium tuberculosis ( Mtb ) in 1,556 Peruvian TB patients. We identified a significant association between a human variant in the FLOT1 gene and a u...

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Literature Corpus work: 6cfa7a8b-363b-55bb-9573-1dac824c672c
DOI: 10.1101/2022.02.07.22270622

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