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Chloroquine and VEGF-A<sub>165</sub>-Challenged Retinal Endothelial Cells: Apparent Barrier Stabilization Versus Phenotype Loss

2026-02-24

Abstract excerpt

Various sight-threatening diseases are caused by an elevated permeability of the layer of retinal microvascular endothelial cells (REC), induced by high intravitreal levels of vascular endothelial growth factor-A165 (VEGF-A165). Barrier impairment is accompanied by an altered expression of proteins restricting para- and transcellular flow, counteracted by inhibition of VEGF-A-signaling. Here we investigated whethe...

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Literature Corpus work
6ce472ce-2f62-5d81-8bf4-eb178de2b7d0
DOI
10.20944/preprints202602.1455.v1
Open publication

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Chloroquine and VEGF-A<sub>165</sub>-Challenged Retinal Endothelial Cells: Apparent Barrier Stabilization Versus Phenotype LossDOI 10.20944/preprints202602.1455.v1
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