Article
Genomic methods for clinical and translational pain research.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2012
Wang Dan, Kim Hyungsuk, Wang Xiao-Min, Dionne Raymond
Abstract excerpt
Pain is a complex sensory experience for which the molecular mechanisms are yet to be fully elucidated. Individual differences in pain sensitivity are mediated by a complex network of multiple gene polymorphisms, physiological and psychological processes, and environmental factors. Here, we present the methods for applying unbiased molecular-genetic approaches, genome-wide association study (GWAS), and global...
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