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Article

The beta3 subunit of the Na+,K+-ATPase mediates variable nociceptive sensitivity in the formalin test.

Pain - 1 Aug 2009

LaCroix-Fralish Michael L, Mo Gary, Smith Shad B, Sotocinal Susana G, Ritchie Jennifer, Austin Jean-Sebastien, Melmed Kara, Schorscher-Petcu Ara, Laferriere Audrey C, Lee Tae Hoon, Romanovsky Dmitry, Liao Guochun, Behlke Mark A, Clark David J, Peltz Gary, Séguéla Philippe, Dobretsov Maxim, Mogil Jeffrey S

Abstract excerpt

It is widely appreciated that there is significant inter-individual variability in pain sensitivity, yet only a handful of contributing genetic variants have been identified. Computational genetic mapping and quantitative trait locus analysis suggested that variation within the gene coding for the beta3 subunit of the Na+,K+-ATPase pump (Atp1b3) contributes to inter-strain differences in the early phase formalin...

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Identifiers

PMID: 19464798
DOI: 10.1016/j.pain.2009.04.028
PMCID: PMC2744953

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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