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NOTCH gene alterations in metastatic colorectal cancer in the Nationwide Cancer Genome Screening Project in Japan (SCRUM-Japan GI-SCREEN)

2022-03-31

Abstract excerpt

<title>Abstract</title> <p><bold>Purpose</bold> Activated Notch receptor signaling has been implicated in tumor growth and progression in colorectal cancer (CRC). However, the pathogenic relevance of <italic>NOTCH</italic> gene alterations remains unclear. The aim of this study was to clarify mutational landscapes and assess their clinical significance in patients with metastatic CRC.<bold>Methods</bold> Pre-chem...

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Literature Corpus work
6cb35f23-7221-5e23-ad11-4e5d0a0b26ce
DOI
10.21203/rs.3.rs-1493432/v1
Open publication

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NOTCH gene alterations in metastatic colorectal cancer in the Nationwide Cancer Genome Screening Project in Japan (SCRUM-Japan GI-SCREEN)DOI 10.21203/rs.3.rs-1493432/v1
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