Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

NOTCH4 Is a Novel Prognostic Marker that Correlates with Colorectal Cancer Progression and Prognosis

1 Jan 2018

Abstract excerpt

Notch family plays vital role in carcinogenesis and progression of various cancer, however, its clinical significance and prognostic value in colorectal cancer isn't fully investigated. In present study, we first investigated the NOTCH4 expression in The Cancer Genome Atlas (TCGA) (n=361) and GSE39582 (n=474) database and then validated with our own database (n=248). The transcriptional and protein levels of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Genetic factors in colorectal cancer
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30026833
DOI: 10.7150/jca.26359

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

NOTCH4 Is a Novel Prognostic Marker that Correlates with Colorectal Cancer Progression and PrognosisPMID 30026833Read ↗

NOTCH4 regulates colorectal cancer proliferation, invasiveness, and determines clinical outcome of patientsSemantic proximity Read ↗

Prognosis model of colorectal cancer patients based on NOTCH3, KMT2C, and CREBBP mutationsSemantic proximity Read ↗

Identification and Clinical Validation of a Novel 4 Gene-Signature with Prognostic Utility in Colorectal CancerSemantic proximity Read ↗

Identification of Genes Related to Clinicopathological Characteristics and Prognosis of Patients with Colorectal CancerSemantic proximity Read ↗

Frequent Activation of Notch Signaling Pathway in Colorectal Cancers and Its Implication in Patient Survival OutcomeSemantic proximity Read ↗

Unraveling a novel hippo-associated immunological prognostic signature: The contribution of SERPINE1 in facilitating colorectal cancer progression via the notch signaling pathwaySemantic proximity Read ↗

NICD3 regulates the expression of MUC5AC and MUC2 by recruiting SMARCA4 and is involved in the differentiation of mucinous colorectal adenocarcinomaSemantic proximity Read ↗

NOTCH gene alterations in metastatic colorectal cancer in the Nationwide Cancer Genome Screening Project in Japan (SCRUM-Japan GI-SCREEN).Semantic proximity Read ↗

Prognostic role and clinicopathological features of SMAD4 gene mutation in colorectal cancer: a systematic review and meta-analysisSemantic proximity Read ↗

KCNC3 acts as a potential biomarker that is involved in the prognosis and tumor immune microenvironment in colorectal cancerSemantic proximity Read ↗

Prognostic role and clinicopathological features of SMAD4 gene mutation in colorectal cancer: a systematic review and meta-analysis.Semantic proximity Read ↗

BRAF-activated lncRNA predicts gastrointestinal cancer patient prognosis: a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.