Article

mRNA-based generation of marmoset PGCLCs capable of differentiation into gonocyte-like cells

2022-09-20

Abstract excerpt

<h4>Summary</h4> Primate germ cell development remains largely unexplored due to limitations in sample collection and the long duration of development. In mice, primordial germ cell-like cells (PGCLCs) derived from pluripotent stem cells (PSCs) can develop into functional gametes by in vitro culture or in vivo transplantation. Such PGCLC-mediated induction of mature gametes in primates is highly useful for unde...

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Literature Corpus work: 6cb12926-ab00-52b6-9564-9453a6543742
DOI: 10.1101/2022.09.20.508677

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