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Germline specification from pluripotent stem cells

21 Feb 2022

Abstract excerpt

Reproduction is a key event in life guaranteeing the propagation and evolution of a species. Infertility caused by abnormal germ cell development is a topic of extensive concern. Herein, in vitro germline specification studies provide a modeling platform to investigate gametogenesis. The differentiation of pluripotent stem cells (PSCs) into germ cells has been studied for more than 30 years, and there have been...

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PMID: 35189957
DOI: 10.1186/s13287-022-02750-1

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