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In vitro oogenesis from murine premeiotic germ cells using a new three-dimensional culture system

31 Jul 2023

Abstract excerpt

A faithful reconstitution of the complete process of oogenesis in vitro is helpful for understanding the molecular mechanisms, genetics, and epigenetic changes related to gametogenesis; it can also be useful for clinical drug screening, disease research, and regenerative medicine. To this end, given the consensus that murine female germ cells initiate meiosis at E13.5, substantial works have reported the...

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PMID: 37518361
DOI: 10.1038/s41420-023-01577-w

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