Article

HCF-2 inhibits cell proliferation and activates differentiation-gene expression programs

2019-03-14

Abstract excerpt

<h4>ABSTRACT</h4> HCF-2 is a member of the h ost- c ell- f actor protein family, which arose in early vertebrate evolution as a result of gene duplication. Whereas its paralog, HCF-1, is known to act as a versatile chromatin-associated protein required for cell proliferation and differentiation, much less is known about HCF-2. Here, we show that HCF-2 is broadly present in human and mouse cells, and possesses...

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Literature Corpus work: 6c9b3bcf-7530-57a3-8a84-7cd58e01e43e
DOI: 10.1101/577890

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