Article

The SARS-CoV-2 spike protein binds and modulates estrogen receptors

2022-05-23

Abstract excerpt

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein binds angiotensin-converting enzyme 2 (ACE2) at the cell surface, which constitutes the primary mechanism driving SARS-CoV-2 infection. Molecular interactions between the transduced S and endogenous proteins likely occur post-infection, but such interactions are not well understood. We used an unbiased primary screen to profile the...

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Literature Corpus work: 6c8ca191-6067-5f61-b227-e4ccebc10b74
DOI: 10.1101/2022.05.21.492920

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