Article
Structural basis and analysis of hamster ACE2 binding to different SARS-CoV-2 spike RBDs.
Journal of virology - 19 Mar 2024
Niu Sheng, Zhao Zhennan, Liu Zhimin, Rong Xiaoyu, Chai Yan, Bai Bin, Han Pengcheng, Shang Guijun, Ren Jianle, Wang Ying, Zhao Xin, Liu Kefang, Tian Wen-Xia, Wang Qihui, Gao George Fu
Abstract excerpt
Pet golden hamsters were first identified being infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) delta variant of concern (VOC) and transmitted the virus back to humans in Hong Kong in January 2022. Here, we studied the binding of two hamster (golden hamster and Chinese hamster) angiotensin-converting enzyme 2 (ACE2) proteins to the spike protein receptor-binding domains (RBDs) of...
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