Article

A lipocalin mediates unidirectional haem biomineralization in malaria parasites

2020-02-19

Abstract excerpt

<h4>ABSTRACT</h4> During blood stage development, malaria parasites are challenged with the detoxification of enormous amounts of haem released during the proteolytic catabolism of erythrocytic haemoglobin. They tackle this problem by sequestering haem into bioinert crystals known as haemozoin. The mechanisms underlying this biomineralization process remain enigmatic. Here, we demonstrate that both rodent and hum...

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Literature Corpus work: 6c80c7b8-e3bd-59df-8ebc-88ccdb9a2981
DOI: 10.1101/2020.02.18.954289

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