Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Synthetic Plasmodium-Like Hemozoin Activates the Immune Response: A Morphology - Function Study

8 Sept 2009

Abstract excerpt

Increasing evidence points to an important role for hemozoin (HZ), the malaria pigment, in the immunopathology related to this infection. However, there is no consensus as to whether HZ exerts its immunostimulatory activity in absence of other parasite or host components. Contamination of native HZ preparations and the lack of a unified protocol to produce crystals that mimic those of Plasmodium HZ (PHZ) are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Computational Drug Discovery Methods
Share to Malaria Research and Control
Share to Mosquito-borne diseases and control

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19742308
DOI: 10.1371/journal.pone.0006957

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Synthetic Plasmodium-Like Hemozoin Activates the Immune Response: A Morphology - Function StudyPMID 19742308Read ↗

A lipocalin mediates unidirectional haem biomineralization in malaria parasitesSemantic proximity Read ↗

Chemical propulsion of hemozoin crystal motion in malaria parasitesSemantic proximity Read ↗

Hemozoin induces Malaria via activation of DNA damage, p38 MAPK and Neurodegenerative Pathways in Human iPSC-derived Neuronal Model of Cerebral MalariaSemantic proximity Read ↗

The triumph of good over evil: protection by the sickle gene against malaria.Semantic proximity Read ↗

HNE produced by the malaria parasite<i>Plasmodium falciparum</i>generates HNE–protein adducts and decreases erythrocyte deformabilitySemantic proximity Read ↗

<i>Plasmodium falciparum</i> hemozoin-associated biomolecules induce brain endothelial cell barrier disruption in an in vitro model of cerebral malariaSemantic proximity Read ↗

The hemozoin conundrum: is malaria pigment immune-activating, inhibiting, or simply a bystander?Semantic proximity Read ↗

Cytometry in Malaria—A Practical Replacement for Microscopy?Semantic proximity Read ↗

Dendrimeric template of Plasmodium falciparum histidine rich protein II repeat motifs bearing Asp→Asn mutation exhibits heme binding and β-hematin formation.Semantic proximity Read ↗

Flow cytometric readout based on Mitotracker Red CMXRos staining of live asexual blood stage malarial parasites reliably assesses antibody dependent cellular inhibitionSemantic proximity Read ↗

Physical–Chemical Approach to Identify Local Structural Determinants of Molecular Mechanisms: Case Study of Antimalarial Drug Pyronaridine and Crystal-Growth InhibitionSemantic proximity Read ↗

Observed octameric assembly of a Plasmodium yoelii peroxiredoxin can be explained by the replacement of native "ball-and-socket" interacting residues by an affinity tag.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.