Article

Patient-derived zebrafish xenografts of uveal melanoma reveal ferroptosis as a drug target

2022-11-10

Abstract excerpt

<title>Abstract</title> <p>Uveal melanoma (UM) has a high risk to progress to metastatic disease with a median survival of 3.9 months after metastases detection, as metastatic UM responds poorly to conventional and targeted chemotherapy and is largely refractory to immunotherapy. Here, we present a patient-derived zebrafish UM xenograft model mimicking metastatic UM. Cells isolated from Xmm66 spheroids derived fr...

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Literature Corpus work: 6c76bae1-3b0c-5d8a-954e-5dcd8d5c9d49
DOI: 10.21203/rs.3.rs-2113688/v1

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