Article

Melanin enhances metastatic melanoma colonization by inhibiting ferroptosis

2023-09-11

Abstract excerpt

<title>Abstract</title> <p>Melanoma-associated death is mainly caused by metastatic disease whereby increased melanin levels correlate with decreased melanoma patient survival. Which role melanin plays in melanoma-associated death is unknown. Here, we show that melanin protects circulating melanoma cells from ferroptosis, enhancing their metastatic potential. Melanin levels in patient-derived uveal melanoma cells...

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Literature Corpus work: 0d6ffc2a-126c-57e0-9f75-81f5198b5f3e
DOI: 10.21203/rs.3.rs-3255735/v1

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