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Article

HLA-C mismatching improves outcomes following lung transplantation.

HLA - 1 Jun 2024

Hiho Steven J, Levvey Bronwyn J, Diviney Mary B, Brooks Andrew G, Holdsworth Rhonda, Snell Gregory I, Westall Glen P, Sullivan Lucy C

Abstract excerpt

HLA (HLA) are a major barrier to transplant success, as HLA-A and -B molecules are principal ligands for T-cells, and HLA-C for Killer cell Immunoglobulin-like Receptors (KIR), directing Natural Killer (NK) cell function. HLA-C molecules are designated "C1" or "C2" ligands based on residues 77 and 80, which determine the NK cell responses. Here, we investigated donor/recipient HLA-C mismatch associations with the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38924641
DOI: 10.1111/tan.15544

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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