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CD8+ T cell memory induced by successive SARS-CoV-2 mRNA vaccinations is characterized by shifts in clonal dominance

1 Mar 2024

Abstract excerpt

mRNA vaccines against the spike glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) elicit strong T cell responses. However, a clonal-resolution analysis of T cell responses to mRNA vaccination has not been performed. Here, we temporally track the CD8 + T cell repertoire in individuals who received three shots of the BNT162b2 mRNA vaccine through longitudinal T cell receptor sequencing...

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PMID: 38458195
DOI: 10.1016/j.celrep.2024.113887

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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