Article

Renal arterial dysfunction, impaired pressure natriuresis and salt-sensitivity in a mouse model of Cushing syndrome

2024-12-11

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Cushing Syndrome arises from endogenous overproduction of ACTH by a tumour or is acquired through chronic exposure to glucocorticoid medication. Hypertension is a major complication, increasing cardiovascular risk, but underlying mechanisms are not clearly defined. <h4>Methods</h4> We infused male C57BL/6J mice with ACTH or vehicle for 14-21 days, inducing cardinal features...

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Literature Corpus work: 6bd3a33f-dfa3-51c3-8544-d0c0020e431d
DOI: 10.1101/2024.12.11.625204

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