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Article

Central role of the ramAR locus in the multidrug resistance in ESBL-Enterobacterales.

Microbiology spectrum - 6 Aug 2024

Gravey François, Michel Alice, Langlois Bénédicte, Gérard Mattéo, Galopin Sébastien, Gakuba Clément, Du Cheyron Damien, Fazilleau Laura, Brossier David, Guérin François, Giard Jean-Christophe, Le Hello Simon

Abstract excerpt

The aim of this study was to evaluate the proportion of resistance to a temocillin, tigecycline, ciprofloxacin, and chloramphenicol phenotype called t2c2 that resulted from mutations within the ramAR locus among extended-spectrum β-lactamases-Enterobacterales (ESBL-E) isolated in three intensive care units for 3 years in a French university hospital. Two parallel approaches were performed on all 443 ESBL-E...

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Identifiers

PMID: 38916360
DOI: 10.1128/spectrum.03548-23
PMCID: PMC11302662

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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