Article

Alpha globin gene copy number and incident ischemic stroke risk among Black Americans

2023-03-16

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Introduction</h4> People with African ancestry have greater stroke risk and greater heritability of stroke risk than people of other ancestries. Given the importance of nitric oxide (NO) in stroke, and recent evidence that alpha globin restricts nitric oxide release from vascular endothelial cells, we hypothesized that alpha globin gene ( HBA) deletion would be associated with reduced risk of...

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Literature Corpus work: 6b29dd12-298b-5925-afac-0d970038087e
DOI: 10.1101/2023.03.15.23286908

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