Article
Association of Sickle Cell Trait With Ischemic Stroke Among African Americans: A Meta-analysis.
JAMA neurology - 1 Jul 2018
Hyacinth Hyacinth I, Carty Cara L, Seals Samantha R, Irvin Marguerite R, Naik Rakhi P, Burke Gregory L, Zakai Neil A, Wilson James G, Franceschini Nora, Winkler Cheryl A, David Victor A, Kopp Jeffrey B, Judd Suzanne E, Adams Robert J, Longstreth W T, Egede Leonard, Lackland Daniel T, Taylor Herman, Manson JoAnn E, Howard Virginia, Allison Matthew, Gee Beatrice E, Correa Adolfo, Safford Monika M, Arnett Donna K, Howard George, Reiner Alexander P, Cushman Mary
Abstract excerpt
Importance: African Americans and individuals of African ancestry have a higher risk of stroke compared with non-Hispanic white individuals. Identifying the source of this disparity could provide an opportunity for clinical stroke risk stratification and more targeted therapy. Whether sickle cell trait (SCT) is an indicator of increased risk of ischemic stroke among African Americans is still unclear. Objective:...
Topics
- Black or African American
- Aged
- Brain Ischemia
- Female
- Hemoglobins
- Heterozygote
- Humans
- Incidence
- Male