Article
Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke.
Stroke - 1 Aug 2020
Keene Keith L, Hyacinth Hyacinth I, Bis Joshua C, Kittner Steven J, Mitchell Braxton D, Cheng Yu-Ching, Pare Guillaume, Chong Michael, O'Donnell Martin, Meschia James F, Chen Wei-Min, Sale Michèle M, Rich Stephen S, Nalls Mike A, Zonderman Alan B, Evans Michele K, Wilson James G, Correa Adolfo, Markus Hugh S, Traylor Matthew, Lewis Cathryn M, Carty Cara L, Reiner Alexander, Haessler Jeff, Langefeld Carl D, Gottesman Rebecca, Mosley Thomas H, Woo Daniel, Yaffe Kristine, Liu YongMei, Longstreth William T, Psaty Bruce M, Kooperberg Charles, Lange Leslie A, Sacco Ralph, Rundek Tatjana, Lee Jin-Moo, Cruchaga Carlos, Furie Karen L, Arnett Donna K, Benavente Oscar R, Grewal Raji P, Peddareddygari Leema Reddy, Dichgans Martin, Malik Rainer, Worrall Bradford B, Fornage Myriam
Abstract excerpt
BACKGROUND AND PURPOSE: Stroke is a complex disease with multiple genetic and environmental risk factors. Blacks endure a nearly 2-fold greater risk of stroke and are 2× to 3× more likely to die from stroke than European Americans. METHODS: The COMPASS (Consortium of Minority Population Genome-Wide Association Studies of Stroke) has conducted a genome-wide association meta-analysis of stroke in >22 000...
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