Article

Specification of the interstitial cell lineage in the fetal mouse ovary requires balanced Notch signaling

2026-04-22

Abstract excerpt

The ovary contains two major somatic lineages, granulosa cells and interstitial cells, that arise from progenitors within the coelomic epithelium. However, how these two lineages diverge during ovarian development remains unclear. By analyzing joint single-nucleus transcriptomic and chromatin accessibility profiles of murine ovarian cells at the onset of ovary formation, we identified two somatic progenitor popula...

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Literature Corpus work: 6b180715-2617-5c7e-b4b9-56a7c0793bb2
DOI: 10.64898/2026.04.20.719649

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