Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dissecting the fate of Foxl2-expressing cells in fetal ovary using lineage tracing and single-cell transcriptomics

27 Dec 2022

Abstract excerpt

Gonad somatic cells acquire sex-specific fates during sex determination. In XX gonad, a subset of somatic cells expresses Foxl2 after sex determination which is considered the progenitor of granulosa cells. However, whether these cells also contribute to other cell types at later developmental stages is unknown. In the present study, the cell fate of Foxl2-expressing cells in fetal ovaries was analyzed by lineage...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Renal and related cancers
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36575161
DOI: 10.1038/s41421-022-00492-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dissecting the fate of Foxl2-expressing cells in fetal ovary using lineage tracing and single-cell transcriptomicsPMID 36575161Read ↗

Single-cell transcriptome landscape of developing fetal gonads defines somatic cell lineage specification in humansSemantic proximity Read ↗

Dissecting gonadal cell lineage specification and sex determination during human development using a single-cell transcriptomics approachSemantic proximity Read ↗

Dissecting Human Gonadal Cell Lineage Specification and Sex Determination Using a Single-Cell RNA-Seq ApproachSemantic proximity Read ↗

Comparative single-cell transcriptomic roadmap of mammalian fetal ovarian developmentSemantic proximity Read ↗

Characterization of the human fetal gonad and reproductive tract by single-cell transcriptomicsSemantic proximity Read ↗

Single-cell transcriptomics of the mouse gonadal soma reveals the establishment of sexual dimorphism in distinct cell lineagesSemantic proximity Read ↗

Single-cell RNA sequencing reveals regulation of fetal ovary development in the monkey (Macaca fascicularis)Semantic proximity Read ↗

Single-cell roadmap of human gonadal developmentSemantic proximity Read ↗

Genome-wide identification of FOXL2 binding and characterization of FOXL2 feminizing action in the fetal gonadsSemantic proximity Read ↗

Deciphering the origins and fates of steroidogenic lineages in the mouse testisSemantic proximity Read ↗

Deciphering Cell Lineage Specification during Male Sex Determination with Single-Cell RNA SequencingSemantic proximity Read ↗

Application of Single-Cell RNA Sequencing in Ovarian DevelopmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.