Article

Single-cell transcriptomics of the mouse gonadal soma reveals the establishment of sexual dimorphism in distinct cell lineages

2018-09-07

Abstract excerpt

<h4>Summary</h4> Sex determination is a unique process that allows the study of multipotent progenitors and their acquisition of sex-specific fates during differentiation of the gonad into a testis or an ovary. Using time-series single-cell RNA sequencing (scRNA-seq) on ovarian Nr5a1-GFP + somatic cells during sex determination, we identified a single population of early progenitors giving rise to both pre-granu...

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Literature Corpus work: eaecafbc-a93e-5955-80f3-94701bcaab26
DOI: 10.1101/410407

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