Article

ICAM-1/CD18-mediated sequestration of parasitized phagocytes in cortical capillaries promotes neuronal colonization by Toxoplasma gondii

2024-09-26

Abstract excerpt

<title>Abstract</title> Microbial translocation across the blood-brain barrier (BBB) is a prerequisite for colonization of the central nervous system. The obligate intracellular parasite <italic>Toxoplasma gondii</italic> chronically infects the brain parenchyma of humans and animals, in a remarkably stealthy fashion. Here, we addressed the mechanisms of BBB crossing by intracarotid delivery of parasites and p...

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Literature Corpus work: 6ae67204-91f0-5785-831b-e9d449c6eaf8
DOI: 10.21203/rs.3.rs-5121481/v1

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