Article

Bioengineered 3D microvessels reveal novel determinants of Trypanosoma congolense sequestration

2024-09-25

Abstract excerpt

<title>Abstract</title> <p>In the mammalian host, <italic>Trypanosoma congolense</italic> cytoadheres to the vascular endothelium in a process known as sequestration. Although sequestration influences clinical outcome, disease severity and organ pathology, its determinants and mediators remain unknown. Challenges such as the variability of animal models, the only-recently developed tools to genetically manipulate...

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Literature Corpus work: cf82d442-96b3-5253-8061-ca289ac380ee
DOI: 10.21203/rs.3.rs-5104603/v1

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