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Article

QuASAR-MPRA: accurate allele-specific analysis for massively parallel reporter assays.

Bioinformatics (Oxford, England) - 1 Mar 2018

Kalita Cynthia A, Moyerbrailean Gregory A, Brown Christopher, Wen Xiaoquan, Luca Francesca, Pique-Regi Roger

Abstract excerpt

Motivation: The majority of the human genome is composed of non-coding regions containing regulatory elements such as enhancers, which are crucial for controlling gene expression. Many variants associated with complex traits are in these regions, and may disrupt gene regulatory sequences. Consequently, it is important to not only identify true enhancers but also to test if a variant within an enhancer affects...

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Identifiers

PMID: 29028988
DOI: 10.1093/bioinformatics/btx598
PMCID: PMC6049023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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