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A host-pathogen interaction screen identifies <i>ada2</i> as a mediator of <i>Candida glabrata</i> defences against reactive oxygen species

2018-01-17

Abstract excerpt

Candida glabrata (C. glabrata ) forms part of the normal human gut microbiota but can cause life-threatening invasive infections in immune-compromised individuals. C. glabrata displays high resistance to common azole antifungals, which necessitates new treatments. In this investigation, we identified five C. glabrata deletion mutants ( Δada2, Δbas1 , Δhir3, Δino2 and Δmet31 ) from a library of 196 transcripti...

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Literature Corpus work
6abff1cc-e46f-5652-9cdd-13117b04decd
DOI
10.1101/248955
Open publication

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A host-pathogen interaction screen identifies <i>ada2</i> as a mediator of <i>Candida glabrata</i> defences against reactive oxygen speciesDOI 10.1101/248955
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