Article
Identification of Candida glabrata Transcriptional Regulators That Govern Stress Resistance and Virulence.
Infection and immunity - 16 Feb 2021
Filler Elan E, Liu Yaoping, Solis Norma V, Wang Ling, Diaz Luis F, Edwards John E, Filler Scott G, Yeaman Michael R
Abstract excerpt
The mechanisms by which Candida glabrata resists host defense peptides and caspofungin are incompletely understood. To identify transcriptional regulators that enable C. glabrata to withstand these classes of stressors, a library of 215 C. glabrata transcriptional regulatory deletion mutants was screened for susceptibility to both protamine and caspofungin. We identified eight mutants that had increased...
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