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Article

A Host-Pathogen Interaction Screen Identifies ada2 as a Mediator of Candida glabrata Defenses Against Reactive Oxygen Species.

G3 (Bethesda, Md.) - 4 May 2018

Kounatidis Ilias, Ames Lauren, Mistry Rupal, Ho Hsueh-Lui, Haynes Ken, Ligoxygakis Petros

Abstract excerpt

Candida glabrata (C. glabrata) forms part of the normal human gut microbiota but can cause life-threatening invasive infections in immune-compromised individuals. C. glabrata displays high resistance to common azole antifungals, which necessitates new treatments. In this investigation, we identified five C. glabrata deletion mutants (∆ada2, ∆bas1, ∆hir3, ∆ino2 and ∆met31) from a library of 196 transcription...

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Source

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Identifiers

PMID: 29535147
DOI: 10.1534/g3.118.200182
PMCID: PMC5940155

Genes

ADA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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