Article

Cryo-EM structure of the conjugation H-pilus reveals the cyclic nature of the TrhA pilin

2024-12-31

Abstract excerpt

Conjugation, the major driver of the spread of antimicrobial resistance genes, relies on a conjugation pilus for DNA transfer. Conjugative pili, such as the F–pilus, are dynamic tubular structures, composed of a polymerized pilin, that mediate the initial donor–recipient interactions, a process known as mating pair formation (MPF). IncH are low copy number plasmids, traditionally considered broad host range, which...

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Literature Corpus work: 6abb2d35-c154-5374-91b6-87963e2e0841
DOI: 10.1101/2024.12.30.630807

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