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TraN variants mediate conjugation species specificity of IncA/C, IncH and <i>Acinetobacter baumannii</i> plasmids

2025-11-15

Abstract excerpt

IncA/C and IncH plasmids commonly carry antimicrobial resistance genes, notably bla NDM-1 . Although these plasmids disseminate among Gram-negative pathogens via conjugation, the mechanisms underlying mating pair stabilisation (MPS) and conjugation species specificity remain poorly understood. In IncF plasmids, MPS is mediated by interactions between outer membrane proteins (OMP) encoded by the plasmids in the do...

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Literature Corpus work
a29fb859-0211-5321-ad3e-f9d3706df16d
DOI
10.1101/2025.11.14.688549
Open publication

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TraN variants mediate conjugation species specificity of IncA/C, IncH and <i>Acinetobacter baumannii</i> plasmidsDOI 10.1101/2025.11.14.688549
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