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Article

TraN variants mediate conjugation species specificity of IncA/C, IncH, and Acinetobacter baumannii plasmids.

Journal of bacteriology - 23 Apr 2026

He Shan, David Sophia, Rattle Jaie, Sanchez-Garrido Julia, Low Wen Wen, Wong Joshua L C, Beis Konstantinos, Frankel Gad

Abstract excerpt

IncA/C and IncH plasmids commonly carry antimicrobial resistance genes, notably blaNDM-1. Although these plasmids disseminate among Gram-negative pathogens via conjugation, the mechanisms underlying mating pair stabilization (MPS) and conjugation species specificity remain poorly understood. In IncF plasmids, MPS is mediated by interactions between outer membrane proteins (OMP) encoded by the plasmids in the...

Topics

Acinetobacter baumannii
Plasmids
Conjugation, Genetic
Species Specificity
Genetic Variation
Bacterial Outer Membrane Proteins

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 41854426
DOI: 10.1128/jb.00536-25
PMCID: PMC13104618

Genes

OMP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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