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Article

Definition of a bacterial type IV secretion pathway for a DNA substrate.

Science (New York, N.Y.) - 21 May 2004

Cascales Eric, Christie Peter J

Abstract excerpt

Bacteria use conjugation systems, a subfamily of the type IV secretion systems, to transfer DNA to recipient cells. Despite 50 years of research, the architecture and mechanism of action of the channel mediating DNA transfer across the bacterial cell envelope remains obscure. By use of a sensitive, quantifiable assay termed transfer DNA immunoprecipitation (TrIP), we identify contacts between a DNA substrate...

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Identifiers

PMID: 15155952
DOI: 10.1126/science.1095211
PMCID: PMC3882297

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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