Article
Structure of the Bacterial Sex F Pilus Reveals an Assembly of a Stoichiometric Protein-Phospholipid Complex.
Cell - 8 Sept 2016
Costa Tiago R D, Ilangovan Aravindan, Ukleja Marta, Redzej Adam, Santini Joanne M, Smith Terry K, Egelman Edward H, Waksman Gabriel
Abstract excerpt
Conjugative pili are widespread bacterial appendages that play important roles in horizontal gene transfer, in spread of antibiotic resistance genes, and as sites of phage attachment. Among conjugative pili, the F "sex" pilus encoded by the F plasmid is the best functionally characterized, and it is also historically the most important, as the discovery of F-plasmid-mediated conjugation ushered in the era of...
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